(3-Formyl-2-methoxyphenyl)boronic acid

(3-Formyl-2-methoxyphenyl)boronic acid - Names and Identifiers

Name	(3-formyl-2-methoxyphenyl)boronic acid
Synonyms	3-FORMYL-2-METHOXYPHENYLBORONIC ACID 3-FORMYL-2-METHOXYBENZENEBORONIC ACID 3-Formyl-2-Methoxybenzeneboronic Acid (3-Formyl-2-methoxyphenyl)boronic acid (3-formyl-2-methoxyphenyl)boronic acid 3-FORMYL-2-METHYLOXYBENZENEBORONIC ACID 3-FORMYL-2-METHOXYBENZENEBORONIC ACID 98 Boronic acid, B-(3-formyl-2-methoxyphenyl)- boronic acid, B-(3-formyl-2-methoxyphenyl)- Boronic acid, (3-formyl-2-methoxyphenyl)- (9CI) 3-Formyl-2-methoxyphenylboronic Acid (contains varying amounts of Anhydride)
CAS	480424-49-5
InChI	InChI=1/C8H9BO4/c1-13-8-6(5-10)3-2-4-7(8)9(11)12/h2-5,11-12H,1H3

(3-Formyl-2-methoxyphenyl)boronic acid - Physico-chemical Properties

Molecular Formula	C8H9BO4
Molar Mass	179.97
Density	1.25±0.1 g/cm3(Predicted)
Melting Point	122-125
Boling Point	407.7±55.0 °C(Predicted)
Flash Point	200.4°C
Vapor Presure	2.22E-07mmHg at 25°C
pKa	7.86±0.58(Predicted)
Storage Condition	Inert atmosphere,2-8°C
Refractive Index	1.537

(3-Formyl-2-methoxyphenyl)boronic acid - Risk and Safety

Hazard Symbols	Xi - Irritant
WGK Germany	3
Hazard Note	Irritant/Keep Cold
Hazard Class	IRRITANT

(3-Formyl-2-methoxyphenyl)boronic acid - Introduction

(3-formyl-2-methoxyphenyl)boronic acid is an organic compound with the chemical formula C8H9BO4. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: Usually a white crystalline solid.
-Solubility: Soluble in many organic solvents, such as chloroform, dimethyl sulfoxide, etc.
-Melting point: The melting point is about 154-155°C.
-Stability: relatively stable under conventional experimental conditions.

Use:
(3-formyl-2-methoxyphenyl)boronic acid has a wide range of applications in organic synthesis. It is often used as a substrate or reagent for organic synthesis reactions, mainly for the formation of C- C bonds or C- O bonds. It can be used in the synthesis of aromatic compounds, drugs and pesticides.

Preparation Method:
A simple method for preparing (3-formyl-2-methoxyphenyl)boronic acid is through the reaction of phenylboronic acid and p-tolualdehyde. The specific preparation steps are as follows:
1. A phenylboronic acid solution was prepared by dissolving phenylboronic acid in dry dimethyl sulfoxide (DMSO).
2. Add p-tolualdehyde to the phenylboronic acid solution and react at room temperature.
3. The reaction is usually completed within a few hours to several days. After completion of the reaction, the product can be obtained by rinsing with water or other solvent.

Safety Information:
There is a lack of detailed experimental data on the safety information of (3-formyl-2-methoxygenyl) boronic acid. However, in general, handling chemicals should follow routine laboratory safety measures, such as wearing appropriate personal protective equipment (such as laboratory gloves, protective glasses, and laboratory clothing). At the same time, the compound should be used and stored to avoid contact with fire, high temperature and oxidizing agents. If necessary, further safety assessment by laboratory professionals is recommended.

Last Update：2024-04-09 21:54:55